Structural biologists have been forced to live within the limitations of traditional liquid handlers when planning crystallization experiments. These limitations are eliminated with the Echo liquid handler, which dispenses the diverse range of sparse matrix crystallography fluids in volume increments of 2.5 nL. Using a process called Dynamic Fluid Analysis™, the Echo liquid handler acoustically interrogates each well, and automatically adjusts power requirements to transfer—ensuring precise transfer of hundreds of various crystallography screens with one self-adjusting fluid type.
Key Benefits:
- Dynamic Fluid Analysis guarantees every liquid is dispensed with industry-leading accuracy and precision
- Drop-on-drop performance at final assay volumes as low as 50 nL
- Produce screens on the fly from concentrated stock reagents, simplifying grid screens formulation
- Investigate small molecule binding while minimizing DMSO interference
Literature:
Application Notes
Nanoliter Scale High-Throughput Protein Crystallography Screening Application Note
Protein Crystallography Application Highlight
Featured Posters
Nanoliter Scale High Throughput Protein Crystallography... - SLAS2012
Acoustic Liquid Handling Applied to Protein Crystallography - ACA 2011
Featured Publication
Acoustically mounted microcrystals yield high-resolution X-ray structures. Soares et al., Biochemistry. 2011
Product Brochures
Echo Liquid Handler Product Brochure
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