The John Innes Centre in Norwich, UK, presented information about the Engineering Nitrogen Symbiosis for Africa (ENSA) project at our recent Genomics Symposium in Edinburgh. The aim of the projects, according to Dr. Andy Breakspear, is to integrate the molecular pathways from legumes into cereal crops for better affordability and sustainability.
To achieve their goals, the team uses Golden Gate technology and an automated, multi-gene construct assembly pipeline to produce hundreds of sequence-validated constructs per week, achieving 100% accuracy. Dr. Breakspear explains how automation of the assembly workflow has exponentially increased the number of constructs possible to make per week, and that Labcyte’s Echo® Liquid Handlers and Access™ Workstations are fundamental to this new, accelerated pipeline.
This is an exciting application of synthetic biology to help the developing world and is funded by the Bill and Melinda Gates Foundation. You can watch Dr. Breakspear's presentation video here.