Portrait® 630 Spotter

The Portrait 630 spotter is an automated, non-contact and nozzle-free acoustic transfer system. It is optimized to deposit MALDI matrix and other reagents on tissue sections and other samples for precision MALDI imaging mass spectrometry. Flexible spot-on-spot positioning and timing enable sequential reaction chemistry and improve crystal formation—yielding high-quality, sensitive and reproducible mass spectra.

Precise Reagent Spotting

The Portrait 630 spotter offers maximum control over laboratory experiments. It accommodates a wide range of reagent types, including MALDI matrix solutions, buffers and surfactants. Because the Portrait 630 has no nozzles to clog, it accommodates even the highest concentrations of crystallizing agents.

Fast, Flexible Operation

• Rapid operation, with a cycle of one droplet per spot consuming less than two minutes
• The ability to accommodate a variety of glass and metal targets as well as standard glass microscope slides
• Precise application of reagents and matrix through a full-color CCD imaging system
• The ability to draw grids for whole-tissue mapping or scatter patterns for protein profiling through user-defined spotting patterns
• The capacity to optimize results for different tissue types and experiments through user-adjustable deposition volume, cycle repeats, droplet and cycle timing
• The ability to optimize experimental conditions in a single step by creating different biochemical conditions on different areas of the sample or performing  biochemical reactions by applying reagents sequentially to the same locations
• Superior position precision through drop-on-drop application capabilities and selective specification of target areas