At BEBPA 2019, Biotech Scientists Reported Bioassay Benefits from Echo Liquid Handlers

Written by Allison S on March 26, 2019

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The Labcyte team was delighted to attend this year’s BEBPA US Bioassay Conference in San Pedro, Calif., where scientists from Amgen and Catalent Biologics gave presentations that included data from their use of the Echo Liquid Handler. In both cases, the Echo systems helped to streamline and accelerate their cell-based assay workflows.

Jill Crouse-Zeineddini, Scientific Director at Amgen, spoke about the use of our acoustic droplet ejection technology in regulated testing laboratories, a topic that resonated with the BEBPA audience. Her presentation showed that assay plates are made much faster with the Echo system than with manual or tip-based systems, and that results are “analyst agnostic” — in other words, removing any imprecision introduced by analysts. Crouse-Zeineddini was also pleasantly surprised that the Echo Liquid Handler could produce true replicates via direction dilution.

In another talk, Principal Scientist Mike Sadick from Catalent Biologics spoke about how his company recently incorporated an Echo Liquid Handler for use with the TNFa AlphaLISA and ADCC reporter gene-based bioassays. As he detailed in his presentation, major benefits of the instrument include the ability to use direct dilution (as opposed to serial dilution), miniaturization, and reduction of materials such as microplates. His assessment of results found that the Echo Liquid Handlers’s level of accuracy was on par with manual techniques, while precision was much better with the Echo system than with alternative methods.

Finally, Labcyte’s own Application Scientist Jared Bailey presented a poster at the conference about using the Echo Liquid Handler to miniaturize a Humira/TNFa L929 cytotoxicity bioassay.

We really enjoyed the opportunity to interact with so many scientists involved in cell-based assays at this year’s meeting. If we didn’t see you there, feel free to reach out for more information about how to demo an Echo system in your lab.



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