Labcyte Introduces the Echo 650 and 655 Liquid Handlers

New systems include features recently launched with the award-winning 650T and 655T models

October 16, 2018

Labcyte Inc. today launched the Echo® 650 and 655 Liquid Handlers, which employ the unique capabilities of acoustic droplet ejection (ADE) technology with 2.5 nanoliter transfers. The 650 and 655 microplate-based systems include features to improve usability that were first made available in the recently launched 650T and 655T tube and microplate-enabled products. The 650 and 655 systems, which will be offered in addition to the Echo 500-series Liquid Handlers, are upgradeable to support transfers from Echo qualified acoustic sample tubes.

Launched at the Society of Laboratory and Screening (SLAS) meeting in February and winner of the SLAS 2018 New Product Award, the Echo 650T and 655T Liquid Handlers incorporated several new features in addition to the ability to transfer liquids from Echo Qualified acoustic tubes.

“We recognize that many of our users who work with our 550 or 555 systems are not ready to incorporate acoustic tubes into their workflows but may value the other advancements offered in our 650T and 655T systems,” said Chris Grimley, Vice President of Marketing at Labcyte. “We decided to make those features available to them in these new models, and at the same time provide them the ability to add the tube transfer capability when they are ready for it.”

The new Echo 650 and 655 Liquid Handlers are based on the company’s patented acoustic droplet ejection technology, which uses the gentle energy of sound waves to move liquids at nanoliter resolution with superior precision and accuracy. The technology does not contact the liquid in any way, avoiding the risk for sample loss, carryover or cross-contamination. It also enables assay miniaturization with reliable fluid transfers at volumes as low as 2.5 nanoliters – saving time and cost, all while improving data quality. Echo Liquid Handlers are relied on throughout life science research to revolutionize workflows in drug discovery, genomics, synthetic biology, and precision medicine.

The 600-series Echo systems feature an improved fluidics system with a simplified maintenance procedure. In addition, the new fluidics system no longer requires vacuum assist, resulting in quieter operation. Other improvements include an automated plate height adjustment, eliminating the need for physical microplate inserts, and simplifying robotic integration. These new features improve the overall usability of this next offering of Echo systems and result in less maintenance requirements.

“Echo Acoustic Liquid Handlers have re-shaped life sciences by providing highly accurate, fully automated, touchless, low-volume dispensing of fluids,” said Mark Fischer-Colbrie, President and Chief Executive Officer at Labcyte. “With their high transfer accuracy and precision down to nanoliter volumes and with rapid any-well to any-well transfer capabilities, Echo Liquid Handlers have long been integral to state-of-the-art sample management and high-throughput screening solutions and hundreds of other applications. We are excited to introduce these product line extensions that offer the latest advancements to the broader community.”

The company will be featuring the new systems at the upcoming SLAS Americas Sample Management Symposium in Boston.

About Labcyte Inc.

Labcyte, a global biotechnology tools company headquartered in San Jose, California, is revolutionizing liquid handling. Echo® Liquid Handlers use sound to precisely transfer liquids without contact, eliminating the use of pipettes. Labcyte instruments are used worldwide throughout the pharmaceutical and biotechnology industries, as well as by hospitals, service laboratories, contract research organizations, and academic institutions. Our customers work across a wide spectrum of scientific research, including drug discovery, genomics, proteomics, diagnostics and personalized medicine. Labcyte has 63 U.S. patents and others internationally. For more information, visit