Simplify the creation of combinatorial layouts


Setup Combination Screens Quickly and Easily

Design complex combination screening layouts

When performing combination screens, the management of pick lists, transfer maps, and plate handling protocols becomes complex. The Echo Combination Screen software provides a graphical interface to visually combine dose-response curves, controls, and single concentration transfers into combination screening protocols.

Create combinations to screen for synergistic or antagonistic effects

Source Plate

384-well plate containing stock samples


Samples pooled in combinatorial matrix

Destination Plate

384-well plate with decreasing concentrations of selected samples pooled in specific combinations


Combine curves of any format in 2D and 3D

  • Automatically generate curves from common input information: starting concentration, dilution factor, concentration points, number of controls, and concentration limits
  • Apply multiple curves to plate layouts in row- or column-wise orientations with wrapping and replicates
  • Use pick lists to map samples to curves in the final combination assay layout

Echo Combination Screen Specifications

Description Specifications
Operating system Microsoft Windows 7 (32-bit or 64-bit), or Microsoft Windows 10 64-bit (Windows 7 compatibility mode); Windows.Net Framework 4.62 or greater
CPU Intel® Core™ i5 or later
Memory 4 GB or greater
Network connection 10/100/1000 BaseT (2 network connections are required)
Network protocol TCP/IP
Hard drive 4 GB Free Space Available
Video resolution 1920 x 1080 recommended resolution (1440 x 900 minimum resolution)
Echo Client Software 2.6 or later
Echo.Net Framework 1.7 or later