APPLICATION NOTES
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G124*
High-Throughput Microliter-Sized Cell-Free Transcription-Translatio...
Ryan Marshall, Jonathan Garamella, Vincent Noireaux, Alex Pierson
ABSTRACT
Cell-free transcription-translation systems (TXTL) are becoming reliable tools to rapidly prototype biochemical systems programmed with synthetic gene circuits. H...
2018
PDF | 827.23 KB
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D105
Utilization of the Labcyte MicroClime® Environmental Lid to Reduce...
John Lesnick, Linda Orren, Noёl Ruppert
ABSTRACT
In this study, we demonstrate the benefit of utilizing the Labcyte MicroClime Environmental Lid to reduce edge effects in a functional cell-based assay by measuri...
2018
PDF | 1.31 MB
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G123
Miniaturized 16S rRNA Amplicon Sequencing with the Labcyte Echo® 52...
Jefferson Lai and John Lesnick
ABSTRACT
Our understanding of the microbial communities in human health, metagenomics, and metataxonomics has been growing rapidly in recent years and is being increasingl...
2017
PDF | 3.99 MB
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G122
Echo® System-Enhanced SMART-Seq® v4 for RNA Sequencing
Jefferson Lai, Anna Lehto, John Lesnick and Carl Jarman
ABSTRACT
As the cost of sequencing has continued to decline by orders of magnitude in the past ten years, scientists are enabled to ask deeper and more complex questions a...
2017
PDF | 3.03 MB
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G118
A Method to Streamline and Miniaturize Nextera™ Library Preparation...
John Lesnick
ABSTRACT
The ongoing evolution of next-generation sequencing (NGS) technologies has reduced sequencing costs by orders of magnitude and significantly increased throughput....
2017
PDF | 750.91 KB
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D101
High-throughput Miniaturization of Cytochrome P450 Time-dependent I...
Jing Wang
ABSTRACT
Early assessment of the ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity) properties of drug candidates has become a critical part of modern dr...
2017
PDF | 265.90 KB
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D102
Miniaturization of Cytochrome P450 Time-dependent Inhibition Screen...
Jing Wang
ABSTRACT
Early assessment of the ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity) properties of drug candidates has become a critical part of modern dr...
2017
PDF | 263.68 KB
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G106
Miniaturization of Multiple Displacement Amplification (MDA) of Gen...
Labcyte
ABSTRACT
Advances in whole-genome amplification have enabled sequencing of DNA and RNA from a single cell, or what is commonly called Single-cell Genomics (SCG). SCG has b...
2017
PDF | 281.42 KB
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CUSTOMER APP NOTE
The reliability of assay-ready plates for cell-based screening enab...
Sheraz Gul and Markus Wolf
ABSTRACT
In a collaboration between the Fraunhofer Institute for Molecular Biology and Applied
Ecology (Hamburg, Germany),
and the National University of Ireland (NU...
2017
PDF | 1.01 MB
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D111
Preparation of Mouse Plasma Microsamples for LC-MS/MS Analysis Usin...
Randy Dyer
ABSTRACT
Serial microsampling of animals reduces the overall number of animals sampled and euthanized for toxicology studies. Traditional composite studies in mice can req...
2017
PDF | 287.25 KB
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G121
Effective Miniaturization of Illumina Nextera XT Library Prep for M...
Jefferson Lai, John Lesnick, Noël Ruppert
ABSTRACT
The cost of sequencing per nucleotide has been declining by orders of magnitude over the past ten years; however library preparation of samples for next-generatio...
2017
PDF | 965.62 KB
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D107
High-Precision Cell Dispensing with the Labcyte Echo® Liquid Handler
John Lesnick, Aurore Lejeune-Dodge, Noël Ruppert, Carl Jarman
ABSTRACT
In this technical note, we demonstrate the utility of the Labcyte Echo Liquid Handler to accurately dispense a variety of cell lines to ensure uniformity and viab...