APPLICATION NOTES

Miniaturized PIK3CA Mutational Analysis Utilizing the Labcyte Echo®...DOWNLOAD

G115

Miniaturized PIK3CA Mutational Analysis Utilizing the Labcyte Echo®...

John Lesnick, Linda Orren, Noël Ruppert

ABSTRACT

By combining the acoustic liquid transfer of the Labcyte Echo Liquid Handler with real-time PCR mutation analysis, we have demonstrated a highly efficient, low-co...

2016
PDF | 1.54 MB
Miniaturized Enzo Life Sciences™ HDAC1 Fluor de Lys® Assays Using a...DOWNLOAD

G114

Miniaturized Enzo Life Sciences™ HDAC1 Fluor de Lys® Assays Using a...

Linda Orren, Bonnie Edwards, John Lesnick, Carl Peters

ABSTRACT

Epigenetic targets continue to provide alluring opportunities for drug discovery efforts in the pharmaceutical industry. Such pursuits typically involve the inves...

2016
PDF | 1.06 MB
Optimized NGS Library Preparation with Acoustic Liquid HandlingDOWNLOAD

G113

Optimized NGS Library Preparation with Acoustic Liquid Handling

Jeffrey H. Kim*, Maritza Duarte*, Howard Lee, John Lesnick

ABSTRACT

Radiant Genomics and Labcyte have developed a low-volume, multiplexed next-generation sequencing (NGS) library preparation method using the Echo® 525 Liquid Handl...

2015
PDF | 470.78 KB
Miniaturized EPIgeneous™ HTRF® Assays Using the Echo® Liquid Handler

Bonnie Edwards, Nga Tang, Maggie Nakamura

ABSTRACT

Cisbio’s HTRF assay technology has a wide range of applications in cell-based and biochemical assays. These assays are readily adaptable to high-throughput screen...

2015
PDF | 552.74 KB
Miniaturization of DNA Assembly for Synthetic BiologyDOWNLOAD

G108

Miniaturization of DNA Assembly for Synthetic Biology

Labcyte

ABSTRACT

Traditional DNA assembly methods require reactions of 10-20 microliters per well. The Echo® Liquid Handler can reduce that volume 10-fold, drastically cutting cos...

2015
PDF | 92.44 KB
High Throughput RT-qPCR for Gene Expression Analysis

Labcyte scientists

ABSTRACT

The current standard of accuracy for quantification of gene expression is reverse transcriptase quantitative PCR (RT-qPCR).1 The method offers the highest level o...

2015
PDF | 422.96 KB
Miniaturization of an Epigenetic AlphaLISA® Assay with the Labcyte®...

Edwards B., Wang J., and Peters C

ABSTRACT

Epigenetics continues to emerge as an important target class for drug discovery and cancer research. As programs scale to evaluate many new targets related to epi...

2014
PDF | 1.40 MB
Lower Cost, Higher Throughput Library Preparation with the Echo Liq...DOWNLOAD

G107

Lower Cost, Higher Throughput Library Preparation with the Echo Liq...

Labcyte

ABSTRACT

In this proof of concept study (POC), the Ovation Single Cell RNA-Seq System miniaturization was validated by examining libraries prepared and sequenced at tradit...

2014
PDF | 444.48 KB
Miniaturized AlphaLISA® Assays Using the Echo® Liquid HandlerDOWNLOAD

D104

Miniaturized AlphaLISA® Assays Using the Echo® Liquid Handler

B Edwards, J Wang, C Peters, EJ Dell*

ABSTRACT

Labcyte Echo liquid handlers transfer compounds and reagents at nanoliter volumes without the use of tips or contact. This capability provides the precision and a...

2014
PDF | 359.92 KB
Filling MicroClime® Environmental Lids

Labcyte

ABSTRACT

The Labcyte® MicroClime environmental lid minimizes edge effects and preserves the concentration of solutions in microplate wells. Unlike standard microplate lids...

2014
PDF | 106.77 KB
Miniaturized Drug Sensitivity and Resistance Testing with the Echo®...

Edwards B, Jarman C, Wennerberg K, Yadav B, Pemovska T, Aittokallio T

ABSTRACT

Recently identified associations between variants of cancer genes and drug resistance increase the value for comprehensive drug sensitivity and resistance testing...

2013
PDF | 1.45 MB