APPLICATION NOTES

* Requires registration

Miniaturized Drug Sensitivity and Resistance Testing with the Echo® Liquid Handler and Access™ Workstation

Edwards B, Jarman C, Wennerberg K, Yadav B, Pemovska T, Aittokallio T

ABSTRACT

Recently identified associations between variants of cancer genes and drug resistance increase the value for comprehensive drug sensitivity and resistance testing...

2013
PDF | 1.45 MB
Miniaturization of the KASP™ Genotyping Assay for Maize with the Echo® 525 Liquid HandlerDOWNLOAD

G105

Miniaturization of the KASP™ Genotyping Assay for Maize with the Echo® 525 Liquid Handler

Pierson A

ABSTRACT

Single nucleotide polymorphism (SNP) genotyping of maize samples is commonly performed in agricultural science to aide marker assisted selection, study heterosis...

2013
PDF | 443.93 KB
Assay Assembly for Miniaturized Quantitative PCR in a 384-well Format Using the Echo® Liquid HandlerDOWNLOAD

G102

Assay Assembly for Miniaturized Quantitative PCR in a 384-well Format Using the Echo® Liquid Handler

Labcyte scientists

ABSTRACT

Quantitative PCR (qPCR) has enabled a wide range of real-time applications including comparisons in gene expression, genotyping and SNP analysis. Reductions in sc...

2013
PDF | 358.56 KB
Miniaturizing siRNA Transfection Using the Echo® Liquid HandleDOWNLOAD

G100

Miniaturizing siRNA Transfection Using the Echo® Liquid Handle

C Jarman, C Edwards*, E Bennett*, A Bryne*, A Hoff*, G Bakos*, D Kelleher*, A Long*, A Davies*

ABSTRACT

2013
PDF | 244.60 KB
Miniaturized and High-Throughput Metabolic Stability Assay Enabled by the Echo® Liquid HandlerDOWNLOAD

D103

Miniaturized and High-Throughput Metabolic Stability Assay Enabled by the Echo® Liquid Handler

Wang J

ABSTRACT

Early assessment of ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity properties plays a critical role in the optimization and prediction of pha...

2013
PDF | 158.64 KB
Nanoliter Scale High-Throughput Protein Crystallography Screening with the Echo® Liquid Handler

Edwards B, Harris D

ABSTRACT

The Echo® liquid handler enables protein crystal formation with sitting drop volumes as small as 50 nL. Nanoliter volumes of protein and crystallography reagents...

2013
PDF | 259.15 KB
Miniaturized HTRF® Assays Using the Echo® Liquid Handler

Edwards B, Tang N, Nakamura M

ABSTRACT

Cisbio’s HTRF assay technology has a wide range of applications in cell-based and biochemical assays. These assays are readily adaptable to high-throughput screen...

2013
PDF | 199.45 KB
High Throughput Miniaturization of Cytochrome P450 Inhibition Screening Using the Echo® Liquid Handler

Wang J, Barco J

ABSTRACT

Early assessment of ADMET properties (absorption, distribution, metabolism, excretion and toxicity) of drug candidates has become an essential component of modern...

2013
PDF | 130.11 KB
Automated RT-qPCR Utilizing the Access™ Workstation, the Echo® Liquid Handler, and RealTime Ready™ Reage...

C Glazer, R Dyer

ABSTRACT

RT-qPCR has been increasingly utilized by researchers to quantify mRNA levels. Its widespread use has been limited by an often laborious multi-step process and hi...

2012
PDF | 2.46 MB
Miniaturized Quantitative PCR using the Echo® 555 Liquid Handler and the LightCycler® 1536 Real-Time PCR...DOWNLOAD

CUSTOMER APP NOTE

Miniaturized Quantitative PCR using the Echo® 555 Liquid Handler and the LightCycler® 1536 Real-Time PCR...

C Glazer, M Sonntag, C Jarman, S Datwani, G Sagner, A Tgetgel, G Tellmann

ABSTRACT

Miniaturizing quantitative PCR (qPCR) using 1536-multiwell plates results in increased throughput, reagent savings, and error reduction. However, delivering reage...

2012
PDF | 3.29 MB
Miniaturized Enzymatic Assays with Glycerol

Labcyte scientists

ABSTRACT

The Echo® liquid handlers incorporate Dynamic Fluid Analysis™ to optimize acoustic transfer on-the-fly. Starting with a default setting for a broad fluid class, e...

2012
PDF | 110.60 KB