POSTERS AND PRESENTATIONS

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Efficient Plasmid Validation By Multiplexing and Miniaturizing Illumina Nextera XT with the Echo® 525 Acoustic Liquid Handler

John Lesnick et al.

ABSTRACT

Synthetic biology is an interdisciplinary science with the potential to impact several academic and industrial applications including the creation of novel therapeutics and vaccines, plant science...

2018
PDF | 1.58 MB
Echo-Miniaturized SMART-Seq v4 for RNASeq Applications

Jefferson Lai, et al.

SLAS2018:

ABSTRACT

As the cost of sequencing has continued to decline by orders of magnitude in the past ten years, scientists are enabled to ask deeper and more complex questions about transcriptomics. Consequently,...

2018
PDF | 507.67 KB
Long-Term Compound Storage in Acoustically Enabled Tubes: Theory and Experiment

Carson T. Riche, et al.

SLAS2018

ABSTRACT

Acoustic transfer of compounds between microplates by Echo® liquid handling instruments has facilitated high-throughput drug discovery at a reduced cost. Until now, these workflows used Echo® quali...

2018
PDF | 408.91 KB
Sonoporation: A Novel Method for Mammalian Cell Transfection

Marsha N Blauwkamp PhD, et al.

SLAS2018

ABSTRACT

We present a novel transfection method called sonoporation, which introduces genetic material and proteins into mammalian cells using the acoustic excitation of microbubbles. Antibody-coated micro...

2018
PDF | 486.80 KB
Reduced Animal Usage and Decreased Study Cost through Microsampling Approaches During Preclinical Safety Testing

Rabia Khan, et al.

SLAS2018

ABSTRACT

Pharmacokinetic and pharmacodynamic safety testing relies heavily upon small animal models during the preclinical phase. Promising lead compounds are typically administered to an animal cohort and...

2018
PDF | 308.70 KB
Miniaturized 16S rRNA Amplicon Sequencing for Metagenomic and Microbiome Studies

Jefferson Lai, et al.

SLAS2018

ABSTRACT

Our understanding of the role of the human microbiome in health and disease has been growing rapidly in recent years and is being increasingly elucidated every day. Amplicon sequencing of highly co...

2018
PDF | 294.32 KB
Acoustic Droplet Ejection of Aqueous Solutions from an Acoustic Tube – Enabling qPCR

Carson T. Riche Ph.D, et al.

SLAS2018

ABSTRACT

Acoustic droplet ejection (ADE) is a fluid dispensing technology, whereby high-frequency sound waves are focused on the surface of a fluid to eject nano- and picoliter volumes with high accuracy an...

2018
PDF | 301.86 KB
Secure and Traceable Acoustic Liquid Handling — An Integrated System for Regulated Laboratory Environments

Iain Russell

SLAS2018

ABSTRACT

The Labcyte Key to bioassay success is implementation of multifactorial optimization approaches such as Design of Experiment (DOE) and sample randomization to control for inherent experimental bias...

2018
PDF | 751.69 KB
Reinventing Sample Management: Integrating New Technologies to Develop a Complete Store-to-Assay Solution Utilizing Acoustic Liquid Handling

Justin Jager

SLAS2018

ABSTRACT

In collaboration with AstraZeneca, Brooks Life Sciences and Titian Software, Labcyte has developed a fully automated system that combines new acoustic tube and acoustic liquid handling technologies...

2018
PDF | 1.09 MB
Miniaturization of a Five Piece PIK3CA Plasmid Assembly by Utilizing NEBuilder® HiFi DNA Assembly Cloning Kit and the Labcyte Echo® 525 Liquid Handler

Jared Bailey, et al.

SLAS2018

ABSTRACT

The ability to rapidly progress from a theoretical DNA construct to a testable plasmid has been a large focus for process improvement within the field of synthetic biology since its inception. Ther...

2018
PDF | 334.37 KB
Combining Tube-based Storage with New Acoustic Liquid Handling Technology to Dramatically Increase Sample Management Efficiency

Iain Russell, et al.

SLAS2018

ABSTRACT

Traditional sample management and high throughput screening has relied heavily on high density microplates for compound storage and tip-based liquid handling solutions for processing. Drawbacks of...

2018
PDF | 4.48 MB
Scaling Workflows for Growing Microbiome Applications

Jefferson Lai, et. al.

ABSTRACT

Our understanding of the role of the human microbiome in health and disease has been growing rapidly in recent years and is being increasingly elucidated every day. Amplicon sequencing of highly...

2017
PDF | 768.67 KB